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The evolution of fillers: injecting the dermis
The Evolution of Fillers: Injecting the Dermis
Description
Book Introduction
Acellular dermal matrix (ADM) injection, unlike conventional synthetic fillers (e.g., hyaluronic acid, CaHA, PLLA, PDLLA, etc.), is a regenerative injectable graft developed by decellularizing and micronizing human-derived dermal tissue. ADM filler is differentiated from existing fillers in that it preserves the extracellular matrix (ECM), including collagen, elastin, glycosaminoglycans (GAGs), and various growth factors, and thus has a fundamental healing mechanism that goes beyond simple volume augmentation and induces tissue regeneration, angiogenesis, and cellular infiltration.
I am excited and thrilled to introduce this new treatment.

In particular, areas of thin skin such as neck wrinkles, dark circles, sunken scars, and fine wrinkles are known to be at high risk for Tyndall effect, abnormal swelling, and vascular complications when hyaluronic acid filler is administered.
In contrast, Human Injectable ADM (Hi-ADM) filler provides a structural scaffold for the dermis-subcutaneous tissue, thereby demonstrating stable and natural effects even on thin skin, and can be expected to have additional effects such as skin texture improvement through ECM remodeling, enhanced moisture retention, and promotion of long-term collagen synthesis.

Additionally, high-resolution ultrasound and Doppler-based pre-planning techniques further enhance safety and precision in all procedures, not just ADM fillers.
In particular, in high-risk anatomical areas such as the infraorbital hollow, tear trough, and neck folds, low-pressure, retrograde injection using a cannula after confirming the location and thickness of blood vessels, lymphatic vessels, and retaining ligaments has become a key strategy to increase safety and predictability.

index
Chapter 1. What is ADM?

Chapter 2.
What is decellularization?

Chapter 3.
Learn more about decellularization methods

Chapter 4.
Learn more about the representative injection-type Hadm

Chapter 5.
Practical Treatment Guide

Chapter 6.
Various concentrations (%), various indications

Chapter 7.
Horizontal wrinkle treatment

Chapter 8.
Tear trough surgery

Chapter 9.
A new concept in ADM injection for scar treatment

Chapter 10.
Water light injection

Chapter 11.
vaginal filler

Chapter 12.
Penis enlargement filler

Chapter 13.
Chin filler

Chapter 14.
Forehead filler

Chapter 15.
Fine Wrinkle Treatment: Mouth Corners, Nasolabial Folds, Marionette Lines


conclusion

Publisher's Review
This book comprehensively covers the definition, mechanism, clinical utility, practical treatment protocols, various concentration and mixing strategies, ultrasound guidance, and safe injection techniques of ADM fillers, and aims to deeply examine the new treatment paradigm that ADM fillers offer, especially in clinically challenging areas such as neck wrinkles and tear troughs.
GOODS SPECIFICS
- Date of issue: November 15, 2025
- Page count, weight, size: 272 pages | 152*225mm
- ISBN13: 9791170683797

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